Working Memory
Cortex
Sensory information in a temporal sequence is processed as a collective unit by the nervous system. The cellular mechanisms underlying how sequential inputs are incorporated into the brain has emerged as an important subject in neuroscience.
Here, we hypothesize that information-bearing (IB) signals can be entrained and amplified by a clock signal, allowing them to efficiently propagate along in a feedforward circuit.
IB signals can remain latent on individual dendrites of the receiving neurons until they are read out by an oscillatory clock signal. In such a way, the IB signals pass through the next neurons along a linear chain.
This hypothesis identifies a cellular process of time-to-space and sound-to-map conversion in primary auditory cortex, providing insight into a mechanistic principle underlying the representation and memory of temporal sequences of information.
Learning & Memory
Hippocampus
After an unexpected accident occurred to Henry Molaison(H.M.), hippocampus has been illuminated as the brain structure mediating memory. With the discovery, many researchers were able to investigate cognitive function such as learning and memory by studying hippocampus.
Long term memory is the memory that does not disappear shortly. (a) This kind of memory can be divided to several categories based on the possibility of clear description and then relation in time. (b) Overall brain anatomy of the rodent is illustrated including hippocampus and a lamellar structure. (c) The most famous pathway, called tri-synaptic circuit (DG → CA3 → CA1), is described.